Extending gene ontology in the context of extracellular RNA

Mikrovesiklar - Microvesicles - qaz.wiki

Further support for the role of exosomes (and possibly MVs) in mediating the systemic benefits of exercise comes from the fact that the majority of the previously reported myokines/exerkines are found in extracellular vesicles databases (Vesiclepedia and ExoCarta). Use Case 2 Part 2: The exRNA Atlas, DEseq and exceRpt pipelines, Vesiclepedia, and Pathway Analysis (pdf, data, article) Use Case 3: Biomarker Potential and Limitations of Circulating miRNA (pdf, pptx, data, article) Education. Here you will find links to online seminars, journal clubs, and classes on exRNA and extracellular vesicle research. We no longer track individual seminars here –– we could not keep up! On Monday and Tuesday April 19–20, 2021, the ERCC hosted a free online workshop on exRNA data analysis.

Mathivanan lab on “Manual curation of ExoCarta and Vesiclepedia – Compendiums of extracellular microvesicles”, from November 2011- January 2012. ExoCarta, an exosome database, provides with the contents that were identified in exosomes in multiple organisms. Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here ExoCarta will be active even after the release of Vesiclepedia and will become a primary resource for high-quality exosomal datasets.

three online databases (ExoCarta, Vesiclepedia and EVpedia). For each database, the pro-teins found in exosomes were collected and a list of proteins/corresponding genes present was produced for each bioﬂuid.

Exosom-orkestrerad Hypoxisk Tumörmikromiljö

2016-02-22 · ExoCarta † was initially described in 2009 , and since its launch, two more databases (Vesiclepedia and EVpedia ) have been described. While both Vesiclepedia and EVpedia catalogue data from multiple types of extracellular vesicles, ExoCarta is a primary resource of exosomal cargo [15] and contains annotations on the isolation and characterization methods. Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into the extracellular microenvironment.

Extending gene ontology in the context of extracellular RNA

Data deposited to ExoCarta can also be accessed through Vesiclepedia; however, only high quality exosomal datasets deposited to Vesiclepedia can be accessed through ExoCarta. Here, we describe Vesiclepedia, a manually curated compendium of molecular data (lipid, RNA and protein) identified in different classes of EVs. Currently, Vesiclepedia comprises 35,264 protein, 18,718 mRNA, 1,772 miRNA and 342 lipid entries encompassed from 341 independent studies that were published over the past several years. 2016-02-22 · ExoCarta † was initially described in 2009 , and since its launch, two more databases (Vesiclepedia and EVpedia ) have been described. While both Vesiclepedia and EVpedia catalogue data from multiple types of extracellular vesicles, ExoCarta is a primary resource of exosomal cargo [15] and contains annotations on the isolation and characterization methods. Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into the extracellular microenvironment. Based on the mode of biogenesis, EVs can be classified into three broad classes (i), ectosomes or shedding microvesicles (ii), exosomes and (iii), apoptotic bodies.

Please share how this access benefits you. Your story matters Citation Kalra, Hina, Richard J. Simpson, Hong Ji, Elena Aikawa, Peter Altevogt, Philip Askenase, Vincent C. Bond, et al. 2012 2018-01-04 Vesiclepedia: VP_9088: ExoCarta: ExoCarta_9088: Entrez Gene: 9088: HGNC: 29650: MIM: 602474 PKMYT1 identified in extracellular vesicles derived from the following tissue/cell type: Colorectal cancer cells [Microvesicles] More >>> 19930720 : Glioblastoma cells [Microvesicles] More >>> 19011622 Table 9: Distribution of Exosomes Isolation Procedures in the Studies Cataloged in ExoCarta Table 10: Statistics of Data Cataloged in ExoCarta, 2012 and 2017 Table 11: Statistics of Data Cataloged in Vesiclepedia, 2012 and 2017 Table 12: Statistics of Data Cataloged in EVpedia, 2018 Table 13: Comparison of Databases for Exosome Studies Exosomes are cell-derived vesicles with the size of 50-150 nm, that are present in many and perhaps all biological fluids, including blood, cerebrospinal fluid, saliva, urine, and cultured medium of cell cultures.Exosomes contain various molecular constituents of their cell of origin, including proteins, DNA and various types of RNA. 2019-05-28 As compared to Vesiclepedia and Exocarta databases, plasma sEVs isolated by the new procedure kept 584 previously identified sEVs-associated proteins and 360 other proteins that have not been detected before. Detailed analysis suggested that more kinds of sEVs biomarkers, such as CD9, ALIX, and FLOT1, John Tanner Wilson.
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On Monday and Tuesday April 19–20, 2021, the ERCC will host a free online workshop on exRNA data analysis. There are three target audiences: experimentalists generating exRNA-seq data, computational and MORE Researchers at La Trobe University have created Vesiclepedia, a web-based compendium of RNA, proteins, lipids and metabolites that are identified in EVs from both published and unpublished studies. Currently, Vesiclepedia contains data obtained from 1254 EV studies, 38 146 RNA entries, 349 988 protein entries and 639 lipid/metabolite entries. 2018-01-04 · Some articles were collected from two publicly available resources, ExoCarta and Vesiclepedia , which are two manually curated databases specialized in collecting information on extracellular vesicles. 2016-04-12 · Of the 519 mass spectrometry identifications, 517 were used for this analysis as there were two sets of proteins for which a single gene name was used by the Exocarta and Vesiclepedia databases to 2of14 BADHWARET AL. Inthelastdecadeorso,EVs,particularlybrain-secretedEVs(BEVs) isolatedfrombloodhaveemergedasanovelplayerinAlzheimer’sdis-ease (AD) progression We compared all the proteins identified in our study to those known vesicular proteins in the Exocarta (38, 39) and Vesiclepedia databases (40, 41).

Further support for the role of exosomes (and possibly MVs) in mediating the systemic benefits of exercise comes from the fact that the majority of the previously reported myokines/exerkines are found in extracellular vesicles databases (Vesiclepedia and ExoCarta). Similarly, mass spectrometry (PRIDE 18, PeptideAtlas 19, Peptidome 20 and Human Proteinpedia), immunohistochemistry (HPA and Human Proteinpedia), exosome (ExoCarta 21, Vesiclepedia 22), colorectal cancer (Colorectal Cancer Database), plasma (Plasma Proteome Database 23), post-translational modification (PhosphositePlus 24, HPRD, Human Proteinpedia and UniProt) databases … On Monday and Tuesday April 19–20, 2021, the ERCC will host a free online workshop on exRNA data analysis. There are three target audiences: experimentalists generating exRNA-seq data, computational and data scientists who have worked with those groups to … 2017-09-25 We compared all the proteins identified in our study to those known vesicular proteins in the Exocarta (38, 39) and Vesiclepedia databases (40, 41).
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Exosom-orkestrerad Hypoxisk Tumörmikromiljö

As exosomes contain RNA, proteins and lipids, there is a significant interest in characterizing the molecular cargo of exosomes. Data deposited to ExoCarta can also be accessed through Vesiclepedia; however, only high quality exosomal datasets deposited to Vesiclepedia can be accessed through ExoCarta.

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Exosomes A Clinical - tusconfcourchi.webblogg.se

With ''Browse'' menu. Fig. 3. Gene Ontology enrichment and network Organisms, 1, 14. Sample types, 21, 47. Visualization tool, No, Yes. External data , ExoCarta, ExoCarta and Vesiclepedia. **Text-mining-assisted curation, No PeptideAtlas19, Peptidome20 and Human Proteinpedia), immunohistochemistry (HPA and Human Proteinpedia), exosome (ExoCarta21, Vesiclepedia22), ExoCarta is a manually curated compendium of exosomal proteins, RNA and lipids. Vesiclepedia is a manually curated and community annotation driven 3 Sep 2019 Vesiclepedia (Version 3.1, 2017) and Exocarta (July 2015) were downloaded to map previously reported EV proteins.